The Different Types and Health Benefits of Probiotics

This is part of our Ultimate Guide to Private Label Probiotics, a complete overview of the benefits of probiotic supplementation for consumers, some of the different strains and their specific uses, the process of responsibly manufacturing a probiotic product, and what to look for when choosing a probiotic manufacturer.


Executive Summary

Probiotic names carry three descriptors, genus, species and strain, and the differences among them are what separate one private label probiotic from another. Because strain and species differences mean two probiotics from the same genus can differ in what they offer a formula, strain-level detail is worth settling early when briefing a probiotic contract manufacturer. Lactobacillus and Bifidobacterium are the two most common genera, joined by Streptococcus thermophilus and the yeast Saccharomyces boulardii among the organisms most often seen in foods and supplements. A working command of how these organisms are classified and named helps product developers select strains, read labels accurately and position a probiotic line with confidence.

Key Takeaways

  • Strain-level detail belongs in the product brief, because species and strains within one genus can differ in the properties they bring to a formula.
  • Lactobacillus and Bifidobacterium are the genera to know first, as the two genera consumers meet most often and researchers study most.
  • Label names are shorthand for genus, species and strain, and although Lactobacillus was reorganized into new genera in 2020, supplement labels still commonly use the familiar names.

For brands developing private label probiotics, the name on a culture works as a specification: it is the detail that tells a dietary supplement contract manufacturer exactly which organism belongs in the formula. When probiotic cultures are listed on a product, such as a supplement or a food panel, they are typically listed with three separate descriptors in their name. These descriptors represent the genus, species, and strain of the culture. For example, on an average yogurt or dietary supplement container, the probiotic might be listed as such: “Lactobacillus acidophilus UALa-01™”.

“Lactobacillus” is the genus, “acidophilus” is the species and “UALa-01™” is the strain of bacteria.

Sometimes these names will be abbreviated on a label or food panel (as some of the names can be quite long). For example “Lactobacillus acidophilus” is sometimes written simply as “acidophilus”. Or, the genus Bifidobacterium or Lactobacillus might be abbreviated as B. or L. and combined with the individual species name, such as acidophilus. (So this example would be listed as “L. acidophilus”.) 

Different probiotics may have the same genus, but differences in the strain and species allow them to provide unique health benefits.†

Classifying Probiotics

Abstract illustration of colored lines branching into three groups, suggesting how probiotics are classified by genus, species and strain
  • Genus: A genus is a class of similar things, especially a group of animals or plants that includes several closely related species. In our example, the genus shares its name, “Lactobacillus”, with several other species, but their mutual traits are fairly general.
  • Species: A species is a class of plants or animals whose members have the same main characteristics, and are able to breed with each other. In our example, the species shares its name, “acidophilus”, with several other strains, but they begin to vary much more. Different species of probiotics can have different abilities, and provide different health benefits.†
  • Strain: A strain of a germ, plant, or other organism is a particular type of it. In our example, the strain is “UALa-01™”, and is different from the others. Some strains are completely unique in their properties, offering benefits that no other strains do.†

The two most common genera in probiotics are Lactobacillus and Bifidobacterium. Each of these genera contains several different strains that are beneficial for your gut and overall health.† It is the strains of these two main genera which are the most commonly recognized, most commonly consumed, and also the most studied. 

Lactobacillus Species

Illustration of rod-shaped Lactobacillus bacteria in orange and red on a yellow surface

As of 2019, the genus Lactobacillus was made up of over 237 species (and 29 subspecies). In 2020, scientists reorganized the Lactobacillus genus into several new genera, but supplement labels still commonly use the familiar names listed below. This genus of bacteria contains strains that produce lactase, the enzyme that breaks down lactose, or milk sugar. These bacteria also work to produce lactic acid, which helps to control the population of bad bacteria, serves as muscle fuel, and increases the body’s absorption of minerals.† Following are some of the most important Lactobacillus strains, with some of their key benefits:

  • Lactobacillus acidophilus. In addition to playing an especially important role in maintaining good digestive health, L. acidophilus has been shown to support the immune system’s normal response to everyday challenges.†
  • Lactobacillus casei. L. casei helps to support normal, healthy cholesterol levels, and a properly functioning digestive system.† It also supports digestive comfort for people young and old, whether traveling or at home.†
  • Lactococcus lactis. L. lactis, like its counterpart L. casei, offers many of the same benefits but it has also been studied for supporting healthy blood pressure.† 
  • Lactobacillus paracasei. L. paracasei is often thought to be one of the most beneficial strains for aiding in digestive function.† Research has also shown that L. paracasei supports the immune system and the body’s natural healing processes.†
  • Lactobacillus plantarum. L. plantarum is an exceptional strain, as it produces its own metabolites that are antibacterial. This helps the body to naturally maintain a balanced microbial environment, helping to support overall immunity.† 
  • Lactobacillus rhamnosus. This strain is particularly beneficial to women’s health, as it is not only beneficial in digestion, but also helps to nourish and support vaginal microflora to support urinary tract functions.† 
  • Lactobacillus fermentum. In addition to helping to improve resistance and supporting the immune system, L. fermentum may also play an important role in supporting proper weight management through the gut-brain axis.†
  • Lactobacillus bulgaricus. This is one of the first probiotic strains ever studied. Some of the many researched benefits of L. bulgaricus include the ability to support normal, healthy cholesterol levels, nourish the intestinal tract, and maintain the integrity of the immune system.†
  • Lactobacillus gasseri. In addition to providing benefits associated with weight loss, inflammation, and cholesterol, L. gasseri provides several other potential benefits.† It has been shown to support immunity in the elderly, and nourish the respiratory system.†  
  • Lactobacillus reuteri. Like most probiotics, L. reuteri is important in intestinal and digestive health.† Interestingly, a strain of Lactobacillus reuteri has been found to support the production of hormones such as testosterone and oxytocin in animal studies.†

Bifidobacterium Species

Illustration of rod-shaped Bifidobacterium bacteria in purple and blue

As of 2019, the genus Bifidobacterium was made up of 80 species and subspecies. They are among the first microbes to colonize the human gastrointestinal tract (appearing within days of birth, especially in breastfed infants), and make up most of the healthy bacteria in the colon. Bifidobacterium species are thought to support the immune system, and to limit the growth of harmful bacteria in the intestine.† Following are some of the most important Bifidobacterium strains, with some of their key benefits:

  • Bifidobacterium bifidum. The strain B. bifidum was first identified over 60 years ago, in infant intestines. It occurs naturally in the bodies of all humans, but factors such as diet, stress, infection, and antibiotics can deplete its numbers. Several high-quality studies on B. bifidum have explored its role in supporting digestive comfort and immune response.†
  • Bifidobacterium breve. B. breve is one of the most helpful probiotic bacteria in the human body.† It is unique in its ability to compete with other harmful bacteria due to the large variety of molecules that it can digest. This powerhouse strain helps to support regularity and digestion.†
  • Bifidobacterium lactis. This strain is one of the most versatile and hardest working, as it supports normal healthy cholesterol levels, and supports the integrity of the intestinal tract, which is key to supporting overall digestive wellness and proper nourishment.†
  • Bifidobacterium longum. Unlike some probiotics, B. longum isn’t affected by stomach acid, bile, pH fluctuations, or the passage through the gastrointestinal tract. B. longum benefits the body by helping to ease common, occasional gastrointestinal discomfort associated with everyday stress.†
  • Bifidobacterium infantis. This strain of probiotic can fight against the harmful bacteria in foods and is beneficial to supporting regularity, calcium absorption, and proper kidney function.†

Other Probiotic Species

Illustration of chains of round Streptococcus thermophilus cells in pink

Streptococcus Species

We mostly are familiar with the word “Streptococcus” when thinking of Strep Throat. In reality, Streptococcus is yet another beneficial genus of probiotics. 

  • Streptococcus thermophilus. S. thermophilus is a powerful probiotic strain that has well-researched health benefits associated with immunity and digestion.† This strain also produces lactase, which can aid in the digestion of dairy for those with a sensitivity to lactose.†

Yeast

The word “yeast” may often carry negative associations when considering the body. There is one type of yeast, however, that actually functions like a probiotic.  

  • Saccharomyces boulardii. S. boulardii has been recommended by doctors for decades to support digestive regularity.† It has also been shown to help support the integrity of the intestinal lining, and to help modulate different parts of the immune system.†

There are many other genera, species, and strains of probiotics. The several mentioned here are the ones most commonly seen in foods and supplements. Although research is ongoing, it is clear that probiotics can provide various health benefits.† Taking the right type of probiotics may help in supporting specific wellness goals and overall health.†

Frequently Asked Questions About Probiotic Strains

Next: ➤ Learn More About the Importance of Prebiotics in Private Label Probiotic Supplements.

Learn more about the next evolution in private label probiotics: advanced blends and targeted formulas

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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